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HIV is not the most dangerous STI's. HPV(Human Papilloma Virus) Human papillomavirus is the most common sexually transmitted infection. Most sexually active men and women being exposed to the virus at some point during their lifetime. The virus is common in the United States and there are approximately 14 million newly diagnosed cases of human papillomavirus (HPV) annually. There are different types of HPV. Some can lead to genital warts and others can cause some types of cancer. Each year, around 19,400 women and 12,100 men in the U.S. are affected by cancers that stem from HPV. Vaccines can protect against infection. In this article, we will explain what HPV is, how it is passed between people, any symptoms that could occur, and information about treatment, vaccines, and prevention. Fast facts on HPV Here are some key points about human papillomavirus. More detail and supporting information is in the main article. Most sexually active men and women will contract the HPV virus at ...